MME anticorps

N° du produit ABIN6937870

Cet anticorps anti-MME Monoclonal Souris (Clone MME-1620) (ABIN6937870) détecte spécifiquement MME dans WB, FACS et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MME anticorps (ABIN6937870)

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MME est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: MME-1620

Détail du produit anti-MME anticorps

Fonction: CD10 (Membrane Metalloendopeptidase) Antibody

Specificité: Recognizes a 100 kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human CD10 protein (MME)

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Ramos cells (FACS/IF). Jurkat or LnCap lysates (WB). Kidney (IHC).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MME

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation: MME

Classe de substances: Chemical

Sujet:

Atriopeptidase, Common acute lymphocytic leukemia antigen (CALLA), Enkephalinase (EPN), gp100, Membrane metalloendopeptidase (MME), Neprilysin, Neutral endopeptidase (NEP), Skin fibroblast elastase (SFE)

Ramos cells (FACS/IF). Jurkat or LnCap lysates (WB). Kidney (IHC).

Poids moléculaire: 100kDa

ID gène: 4311, 307734

UniProt: P08473

Pathways: Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration