MMP2 anticorps (AA 444-575)

N° du produit ABIN6937878

Détail du produit anti-MMP2 anticorps

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Épitope: AA 444-575

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP2 est non-conjugé

Application: Western Blotting (WB)

Specificité: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human MMP2 protein fragment (aa 444-575) (exact sequence is proprietary)

Clone: MMP2-1501

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Western Blot (1-2 μg/mL) Optimal dilution for a specific application should be determined.

Positive_Control: U-138 MG or U-87 MG cells. Placenta or Colon Carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur MMP2

Antigène: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Autre désignation: MMP2 (MMP2 Produits)

Synonymes: anticorps 2-MMP, anticorps CG1794, anticorps DM2-MMP, anticorps Dm2-MMP, anticorps Dmel\\CG1794, anticorps MMP2, anticorps anon-WO0118547.84, anticorps dm-2MMP, anticorps dmmp2, anticorps l(2)02353, anticorps mmp2, anticorps wu:fa99h12, anticorps wu:fk89d01, anticorps fgmmp-2, anticorps Mmp-2, anticorps LOC100135793, anticorps Clg4a, anticorps GelA, anticorps MMP-2, anticorps CLG4, anticorps CLG4A, anticorps MMP-II, anticorps MONA, anticorps TBE-1, anticorps matrix metallopeptidase 2, anticorps Matrix metalloproteinase 2, anticorps matrix metalloproteinase 2, anticorps matrix metalloproteinase-2, anticorps MMP2, anticorps Mmp2, anticorps mmp2, anticorps LOC657982, anticorps LOC100135793

Sujet: 72kD type IV collagenase, CLG4A, Collagenase Type 4 alpha, Collagenase type IV A, Gelatinase A, Gelatinase alpha, Gelatinase neutrophil, Matrix metalloproteinase-2, MMP2, MONA, Neutrophil gelatinase, PEX, TBE-1,MMP2 / Collagenase Type IV A (Tumor Metastasis Marker)
Cellular localisation: Cytoplasmic and Cell Surface

Poids moléculaire: 72kDa (Pro), 63kDa (cleaved)

ID gène: 4313, 513617

UniProt: P08253

Pathways: Activation of Innate immune Response