Moesin anticorps

N° du produit ABIN6937913

Détail du produit anti-Moesin anticorps

Antigène: Moesin (MSN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Moesin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Recognizes 78 kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

Aucune reactivité croisée: Rat (Rattus)

Réactivité croisée (Details): Human. Does not react with rat.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human Moesin protein

Clone: MSN-492

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: K562, HeLa or HUVEC cells. Human uterus, placenta or tonsil.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Moesin

Antigène: Moesin (MSN)

Autre désignation: MSN (MSN Produits)

Synonymes: anticorps CG10701, anticorps D17, anticorps Dmel\\CG10701, anticorps Dmoe, anticorps EMR1, anticorps ERM, anticorps Emr1, anticorps anon-WO03040301.155, anticorps anon-WO03040301.157, anticorps anon-WO03040301.159, anticorps anon-WO03040301.161, anticorps dMoe, anticorps gma, anticorps l(1)G0067, anticorps l(1)G0323, anticorps l(1)G0404, anticorps l(1)G0415, anticorps moe, anticorps moesin/ezrin/radixin homolog mRNA, anticorps cb567, anticorps rdx, anticorps wu:fb14b03, anticorps zgc:85640, anticorps MSN, anticorps C78546, anticorps moesin, anticorps Moesin, anticorps moesin a, anticorps moesin L homeolog, anticorps MSN, anticorps Moe, anticorps msna, anticorps msn.L, anticorps moes, anticorps Msn

Sujet: Membrane-organizing extension spike protein, Moesin/anaplastic lymphoma kinase fusion protein, MSN/ALK fusion,Moesin
Cellular localisation: Cytoplasmic & Cell Surface

Poids moléculaire: 78kDa

ID gène: 4478, 87752

UniProt: P26038

Pathways: Asymmetric Protein Localization