NKX2-8 anticorps (AA 10-123)

N° du produit ABIN6938069

Cet anticorps Souris Monoclonal détecte spécifiquement NKX2-8 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NKX2-8 anticorps (AA 10-123) (ABIN6938069)

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NKX2-8 est non-conjugé

Application: Western Blotting (WB)

Clone: NKX28-2547

Détail du produit anti-NKX2-8 anticorps

Épitope: AA 10-123

Fonction: NKX2.8 Antibody

Specificité: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Western Blot (0.5 μg-1 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: PC3 or MCF-7 cells. Human Liver, Kidney or Thyroid tissue (IHC).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur NKX2-8

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Autre désignation: NKX2-8

Sujet:

Homeobox protein NK 2 homolog H, Homeobox protein NK-2 homolog H, Homeobox protein Nkx 2.8, Homeobox protein Nkx-2.8, NK 2 homolog 8, NK 2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX28_HUMAN, NKX2G, NKX2H, OTTHUMP00000027959

Kidney or Thyroid tissue (IHC)., PC3 or MCF-7 cells. Human Liver

Poids moléculaire: 26kDa

ID gène: 26257, 234763

UniProt: O15522