NKX2-8 anticorps (AA 10-123)

N° du produit ABIN6938070

L’anticorps Souris Monoclonal anti-NKX2-8 a été validé pour WB, ELISA, IHC, Coat et FACS. Il convient pour détecter NKX2-8 dans des échantillons de Humain.

Aperçu rapide pour NKX2-8 anticorps (AA 10-123) (ABIN6938070)

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NKX2-8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Coating (Coat), Flow Cytometry (FACS)

Clone: NKX28-2548

Détail du produit anti-NKX2-8 anticorps

Épitope: AA 10-123

Specificité: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Western Blot (2-4 μg/mL), ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Human Liver, Kidney or Thyroid tissue (IHC).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur NKX2-8

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Autre désignation: NKX2-8

Sujet: Homeobox protein NK 2 homolog H, Homeobox protein NK-2 homolog H, Homeobox protein Nkx 2.8, Homeobox protein Nkx-2.8, NK 2 homolog 8, NK 2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX28_HUMAN, NKX2G, NKX2H, OTTHUMP00000027959,NKX2.8
Cellular localisation: Nuclear and Cytoplasm.

Poids moléculaire: 26kDa

ID gène: 26257, 234763

UniProt: O15522