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PMEPA1 anticorps

PMEPA1 Reactivité: Humain IHC, IHC (f) Hôte: Souris Monoclonal PMEPA1-2696 unconjugated
N° du produit ABIN6938198
  • Antigène Voir toutes PMEPA1 Anticorps
    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
    Reactivité
    • 19
    • 3
    • 2
    Humain
    Hôte
    • 13
    • 6
    Souris
    Clonalité
    • 12
    • 7
    Monoclonal
    Conjugué
    • 17
    • 1
    • 1
    Cet anticorp PMEPA1 est non-conjugé
    Application
    • 13
    • 11
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
    Réactivité croisée (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant full-length human PMEPA1 protein
    Clone
    PMEPA1-2696
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product PMEPA1 Anticorps primaire
  • Indications d'application

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human prostate, breast or renal cell carcinoma tissue (IHC).

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
    Autre désignation
    PMEPA1 (PMEPA1 Produits)
    Synonymes
    anticorps Tmepai, anticorps PMEPA1, anticorps TMEPAI, anticorps zgc:92731, anticorps tmepai, anticorps STAG1, anticorps 2210418I02Rik, anticorps AW455466, anticorps Erg1.2, anticorps N4wbp4, anticorps Stag1, anticorps prostate transmembrane protein, androgen induced 1, anticorps prostate transmembrane protein, androgen induced 1 L homeolog, anticorps Pmepa1, anticorps PMEPA1, anticorps pmepa1, anticorps pmepa1.L
    Sujet
    PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA,PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)
    Cellular localisation: Cell surface. Cytoplasm.
    Poids moléculaire
    32kDa
    ID gène
    56937, 517155
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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