RNLS anticorps (AA 34-235)

N° du produit ABIN6938322

L’anticorps anti-RNLS Monoclonal Souris est utilisé pour la détection de RNLS dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour RNLS anticorps (AA 34-235) (ABIN6938322)

Antigène: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RNLS est non-conjugé

Application: ELISA

Clone: RNLS-1940

Détail du produit anti-RNLS anticorps

Épitope: AA 34-235

Fonction: Renalase (Renal Cell Marker) Antibody

Specificité: Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human RNLS protein fragment (around aa 34-235) (exact sequence is proprietary)

Isotype: IgG2b, kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: 293T cells. Heart or Kidney.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur RNLS

Antigène: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Autre désignation: RNLS

Sujet:

Chromosome 10 open reading frame 59, MAO C, MAO-C, Monoamine oxidase-C, Renalase, Renalase FAD dependent amine oxidase, RNLS

293T cells. Heart or Kidney.

Poids moléculaire: 38kDa

ID gène: 55328, 149849

UniProt: Q5VYX0