S100A1 anticorps

N° du produit ABIN6938330

Cet anticorps Souris Monoclonal détecte spécifiquement S100A1 dans IF et IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour S100A1 anticorps (ABIN6938330)

Antigène: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100A1 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: S1-61

Détail du produit anti-S100A1 anticorps

Specificité: S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the alpha-chain (i.e. in S-100A and S-100B) but not on the beta-chain of S-100 (i.e. in S-100B). This antibody can be used to localize S-100A in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, epithelial and myoepithelial cells of the breast, salivary and sweat glands. Neoplasms derived from these cells also express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.

Réactivité croisée (Details): Human. Others not known.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Purified human full-length native S-100 protein conjugated to methylated BSA

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Immunofluorescence (1-2 μg/mL), ,Immunohistology (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: T98G or A431 or HT-29 Cells. Brain or Melanoma

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur S100A1

Antigène: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Autre désignation: S100A1

Sujet: Bpb, NEF, S100-A1, S100 Alpha Chain, S100 Beta Chain, S100 Calcium Binding Protein A1, S100 Calcium Binding Protein B, S100 Calcium Binding Protein Beta Neural,S100A1 (Melanoma Marker)
Cellular localisation: Cytoplasmic

Poids moléculaire: 10-12kDa

ID gène: 6271, 515715

UniProt: P23297

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins