SELPLG anticorps

N° du produit ABIN6938363

Cet anticorps Souris Monoclonal détecte spécifiquement SELPLG dans FACS et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour SELPLG anticorps (ABIN6938363)

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SELPLG est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PSGL1-1567

Détail du produit anti-SELPLG anticorps

Specificité: CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human SELPLG (CD162) protein

Isotype: IgM kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL) Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat cells. Tonsil.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Purified Ab WITHOUT BSA at 1.0mg/ml

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: SELPLG

Sujet: CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein ligand 1, PSGL1, Selectin P ligand, SELPLG,CD162 (Selectin P Ligand)
Cellular localisation: Cell Surface

Poids moléculaire: 43-120kDa

ID gène: 6404, 591014

UniProt: Q14242