Melanoma gp100 anticorps
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- Antigène Voir toutes Melanoma gp100 (PMEL) Anticorps
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Melanoma gp100 est non-conjugé
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
- Aucune reactivité croisée
- Rat (Rattus)
- Réactivité croisée (Details)
- Human. Horse. Does not react with Rat.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Membranes from a human melanoma metastasis
- Clone
- NKI-beteb
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product PMEL Anticorps primaire
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- Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: SK-MEL-28 cells. Melanoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Autre désignation
- SILV (PMEL Produits)
- Synonymes
- anticorps D12S53E, anticorps ME20, anticorps ME20-M, anticorps ME20M, anticorps P1, anticorps P100, anticorps PMEL17, anticorps SI, anticorps SIL, anticorps SILV, anticorps gp100, anticorps D10H12S53E, anticorps D12S53Eh, anticorps Pmel17, anticorps Si, anticorps Silv, anticorps gp87, anticorps RPE1, anticorps MMP115, anticorps silverb, anticorps silver, anticorps cb397, anticorps fdv, anticorps pmel17, anticorps sb:cb397, anticorps silva, anticorps wu:fc11g11, anticorps wu:fj24g11, anticorps zgc:136622, anticorps premelanosome protein, anticorps premelanosome protein b, anticorps premelanosome protein a, anticorps PMEL, anticorps Pmel, anticorps pmelb, anticorps pmela
- Sujet
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95 kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog,gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)
Cellular localisation: Cytoplasmic - Poids moléculaire
- 90-100kDa
- ID gène
- 6490, 95972
- UniProt
- P40967
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