TCF4 anticorps (AA 365-671)

N° du produit ABIN6938516

Détail du produit anti-TCF4 anticorps

Antigène: TCF4 (Transcription Factor 4 (TCF4))

Épitope: AA 365-671

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TCF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Recognizes a protein of 71kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human TCF4 protein fragment (around aa 365-671) (exact sequence is proprietary)

Clone: TCF4-1705

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells. Human bladder, colon or tonsil.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur TCF4

Antigène: TCF4 (Transcription Factor 4 (TCF4))

Autre désignation: TCF4 (TCF4 Produits)

Synonymes: anticorps E2-2, anticorps ITF-2, anticorps ITF2, anticorps PTHS, anticorps SEF-2, anticorps SEF2, anticorps SEF2-1, anticorps SEF2-1A, anticorps SEF2-1B, anticorps TCF-4, anticorps bHLHb19, anticorps 5730422P05Rik, anticorps ASP-I2, anticorps E2.2, anticorps ITF-2b, anticorps ME2, anticorps MITF-2A, anticorps MITF-2B, anticorps TFE, anticorps Tcf-4, anticorps TCF7L2, anticorps XE2, anticorps Xtcf-4, anticorps Xtcf4, anticorps e2-A, anticorps tcf-4, anticorps transcription factor 4, anticorps transcription factor 4 S homeolog, anticorps TCF4, anticorps Tcf4, anticorps tcf4, anticorps tcf4.S

Sujet: BHLHb19, Class B basic helix-loop-helix protein 19, Immunoglobulin transcription factor 2, ITF-2, PTHS, SEF2, SL3-3 enhancer factor 2, TCF4, Transcription factor 4,TCF4 (Transcription Factor 4)
Cellular localisation: Nucleus. Cytoplasm.

Poids moléculaire: 60kDa

ID gène: 6925, 605153

UniProt: P15884

Pathways: Signalisation WNT, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus