Transferrin Receptor anticorps

N° du produit ABIN6938538

L’anticorps anti-Transferrin Receptor Monoclonal Souris est utilisé pour la détection de Transferrin Receptor dans des échantillons de Humain. Il a été validé pour FACS, IHC et IF.

Aperçu rapide pour Transferrin Receptor anticorps (ABIN6938538)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: TFRC-1396

Détail du produit anti-Transferrin Receptor anticorps

Fonction: CD71 / Transferrin Receptor (TFRC) Antibody

Specificité: It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human TFRC protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen) (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: PC3 cells. Human placenta or breast carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: TFRC

Sujet:

Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

PC3 cells. Human placenta or breast carcinoma.

Poids moléculaire: 85-95kDa (monomer), 190kDa (dimer)

ID gène: 7037, 529618

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis