TTR anticorps

N° du produit ABIN6938683

Détail du produit anti-TTR anticorps

Antigène: TTR (Transthyretin (TTR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TTR est non-conjugé

Application: Western Blotting (WB)

Specificité: Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human full-length protein

Clone: CPTC-TTR-1

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Known_Application: Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HepG2 cell lysate or human kidney or Liver tissue lysate (WB).

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur TTR

Antigène: TTR (Transthyretin (TTR))

Autre désignation: TTR (TTR Produits)

Synonymes: anticorps zgc:103583, anticorps TTR, anticorps LOC100226992, anticorps CTS, anticorps CTS1, anticorps HsT2651, anticorps PALB, anticorps TBPA, anticorps AA408768, anticorps AI787086, anticorps D17860, anticorps prealbumin, anticorps Lr1, anticorps Tbpa, anticorps Prealbumin, anticorps xTTR, anticorps transthyretin (prealbumin, amyloidosis type I), anticorps transthyretin, anticorps Transthyretin, anticorps transthyretin (prealbumin, amyloidosis type 1), anticorps transthyretin-like, anticorps transthyretin L homeolog, anticorps ttr, anticorps TTR, anticorps vpb38, anticorps MRAD2831_RS38185, anticorps Caci_4246, anticorps LOC100226992, anticorps Ttr, anticorps ttr.L

Sujet: Transthyretin, PALB, HsT2651, prealbumin, amyloidosis type 1, ATTR, TBPA, CTS, CTS1, carpal tunnel syndrome 1, thyroxine-binding prealbumin, prealbumin, HEL111, TTR protein, Epididymis luminal protein 111, prealbumin thyroxine binding, senile systemic amyloidosis antibody,Transthyretin (Prealbumin)
Cellular localisation: Secreted. Cytoplasm.

Poids moléculaire: 15kDa

ID gène: 7276, 427202

UniProt: P02766

Pathways: Hormone Transport