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Uroplakin 1B anticorps (AA 109-229)

UPK1B Reactivité: Humain ELISA, Coat, IHC (f) Hôte: Souris Monoclonal UPK1B-3102 unconjugated
N° du produit ABIN6938733
  • Antigène Voir toutes Uroplakin 1B (UPK1B) Anticorps
    Uroplakin 1B (UPK1B)
    Épitope
    • 8
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 109-229
    Reactivité
    • 25
    • 3
    • 2
    Humain
    Hôte
    • 20
    • 5
    Souris
    Clonalité
    • 20
    • 5
    Monoclonal
    Conjugué
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Uroplakin 1B est non-conjugé
    Application
    • 20
    • 18
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.
    Réactivité croisée (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein (exact sequence is proprietary)
    Clone
    UPK1B-3102
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product UPK1B Anticorps primaire
  • Indications d'application

    Known_Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Urinary Bladder.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    Uroplakin 1B (UPK1B)
    Autre désignation
    UPK1B (UPK1B Produits)
    Synonymes
    anticorps MGC81971, anticorps upk1b, anticorps MGC81493, anticorps UPK1B, anticorps TSPAN20, anticorps UPIB, anticorps UPK1, anticorps AI413235, anticorps Tspan20, anticorps UPIb, anticorps Upk1, anticorps uroplakin 1B, anticorps uroplakin 1B S homeolog, anticorps uroplakin 1A S homeolog, anticorps UPK1B, anticorps upk1b.S, anticorps upk1a.S, anticorps upk1b, anticorps Upk1b
    Sujet
    Tetraspanin-20, Tspan-20, TSPAN20, UP1b, UPIb, UPK1B, Uroplakin-1b,Uroplakin 1B (Urothelial Differentiation Marker)
    Cellular localisation: Cell Surface
    Poids moléculaire
    30kDa
    ID gène
    7348, 271580
    UniProt
    O75841
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