Recombinant Uroplakin 1B anticorps (AA 109-229)
Aperçu rapide pour Recombinant Uroplakin 1B anticorps (AA 109-229) (ABIN7857623)
Antigène
Voir toutes Uroplakin 1B (UPK1B) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 109-229
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Expression System
- CHO Cells
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Fonction
- Recombinant Uroplakin 1B (Urothelial Differentiation Marker) Antibody
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Specificité
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.
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Purification
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogène
- Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein (exact sequence is proprietary)
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Uroplakin 1B (UPK1B)
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Autre désignation
- Uroplakin 1B
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Sujet
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Tetraspanin-20, Tspan-20, TSPAN20, UP1b, UPIb, UPK1B, Uroplakin-1b
Urinary bladder (IHC).
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Poids moléculaire
- 30kDa
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ID gène
- 7348, 271580
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UniProt
- O75841
Antigène
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