Recombinant Cadherin-16 anticorps

N° du produit ABIN6939021

Cet anticorps Souris Monoclonal détecte spécifiquement Cadherin-16 dans IHC, WB et FACS. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Lapin et Chien.

Aperçu rapide pour Recombinant Cadherin-16 anticorps (ABIN6939021)

Antigène: Cadherin-16 (CDH16)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat, Lapin, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin-16 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)

Clone: RCDH16-1071

Détail du produit anti-Cadherin-16 anticorps

Fonction: Recombinant Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Antibody

Specificité: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

Réactivité croisée (Details): Human, Mouse, Rat, Rabbit, Dog,

Purification: 200ug/ml of recombinant MAb Purified by Protein A/G.

Immunogène: Recombinant full-length human CDH16 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Positive Control: HEK293 cells. Normal kidney or renal cell carcinoma.

Known Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Cadherin-16

Antigène: Cadherin-16 (CDH16)

Autre désignation: CDH16

Sujet:

Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody

HEK293 cells. Normal kidney or renal cell carcinoma.

Poids moléculaire: 130kDa

ID gène: 1014, 513660

UniProt: O75309