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Recombinant Cadherin-16 anticorps

CDH16 Reactivité: Humain WB, FACS, IHC (f) Hôte: Lapin Monoclonal CDH16-1532R unconjugated Recombinant Antibody
N° du produit ABIN6939024
  • Antigène Voir toutes Cadherin-16 (CDH16) Anticorps
    Cadherin-16 (CDH16)
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 88
    • 40
    • 31
    • 22
    • 21
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 35
    • 1
    Lapin
    Clonalité
    • 48
    • 42
    Monoclonal
    Conjugué
    • 51
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cadherin-16 est non-conjugé
    Application
    • 39
    • 39
    • 38
    • 36
    • 25
    • 19
    • 14
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
    Réactivité croisée (Details)
    Human, Mouse, Rat,
    Purification
    200ug/ml of Ab Purified by Protein A.
    Immunogène
    Recombinant human full-length CDH16 protein
    Clone
    CDH16-1532R
    Isotype
    IgG
    Top Product
    Discover our top product CDH16 Anticorps primaire
  • Indications d'application

    Positive Control: Normal kidney or renal cell carcinoma.

    Known Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA buffer, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    Date de péremption
    24 months
  • Antigène
    Cadherin-16 (CDH16)
    Autre désignation
    CDH16 (CDH16 Produits)
    Synonymes
    anticorps cadherin 16, anticorps CDH16, anticorps Cdh16
    Sujet
    Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody,Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16
    Cellular localisation: Cell Surface and Cytoplasmic
    Poids moléculaire
    130kDa
    ID gène
    1014, 513660
    UniProt
    O75309
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