BAFF anticorps

N° du produit ABIN6939086

Détail du produit anti-BAFF anticorps

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BAFF est non-conjugé

Application: ELISA, Coating (Coat)

Specificité: BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN- BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).

Réactivité croisée (Details): Human,

Purification: 200ug/ml of Ab Purified from rabbit anti-serum by Protein A.

Immunogène: Purified recombinant human CD257 protein

Clone: C257-1638

Isotype: IgG1

Information d'application

Indications d'application:

Positive Control: Jurkat cells. Tonsil and lymph node.

Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Date de péremption: 24 months

Détails sur BAFF

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Autre désignation: TNFSF13B (TNFSF13B Produits)

Synonymes: anticorps BAFF, anticorps BLYS, anticorps CD257, anticorps DTL, anticorps TALL-1, anticorps TALL1, anticorps THANK, anticorps TNFSF20, anticorps ZTNF4, anticorps BAFF-R, anticorps BAFFR, anticorps BROMIX, anticorps CD268, anticorps CVID4, anticorps prolixin, anticorps TNFSF13B, anticorps RGD1561519, anticorps RGD1560810, anticorps BLyS, anticorps D8Ertd387e, anticorps zTNF4, anticorps 2010006P15Rik, anticorps Baffr, anticorps Bcmd, anticorps Bcmd-1, anticorps Bcmd1, anticorps Lvis22, anticorps zgc:172115, anticorps TNF superfamily member 13b, anticorps TNF receptor superfamily member 13C, anticorps tumor necrosis factor (ligand) superfamily, member 13b, anticorps tumor necrosis factor receptor superfamily, member 13c, anticorps tumor necrosis factor superfamily member 13b, anticorps TNFSF13B, anticorps TNFRSF13C, anticorps Tnfsf13b, anticorps Tnfrsf13c, anticorps tnfsf13b

Sujet: ApoL related ligand TALL 1, B lymphocyte stimulator, B-cell-activating factor, BAFF, BLyS, CD257, Dendritic cell-derived TNF-like molecule, DTL, PRO738, TALL-1, THANK, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13b, Tumor necrosis factor ligand superfamily member 20, ZTNF4,CD257 / BAFF / TNFSF13B
Cellular localisation: Cell surface and cytoplasmic

Poids moléculaire: 31kDa (Monomer)

ID gène: 10673, 525157

UniProt: Q9Y275

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response