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CD35 anticorps

CR1 Reactivité: Humain, Babouin, Singe FACS, IHC, IF, StM Hôte: Souris Monoclonal CR1-802 unconjugated
N° du produit ABIN6939179
  • Antigène Voir toutes CD35 (CR1) Anticorps
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    Reactivité
    • 101
    • 24
    • 24
    • 16
    • 15
    • 15
    • 15
    • 4
    • 3
    Humain, Babouin, Singe
    Hôte
    • 66
    • 37
    • 4
    Souris
    Clonalité
    • 76
    • 28
    • 3
    Monoclonal
    Conjugué
    • 46
    • 12
    • 10
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD35 est non-conjugé
    Application
    • 68
    • 38
    • 28
    • 25
    • 21
    • 20
    • 19
    • 17
    • 15
    • 13
    • 13
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
    Specificité
    Recognizes a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein.Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant full-length human CR1 protein
    Clone
    CR1-802
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CR1 Anticorps primaire
  • Indications d'application

    Positive Control: Follicular dendritic cells (FDC) in tonsil.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
    Autre désignation
    CR1 (CR1 Produits)
    Synonymes
    anticorps C3BR, anticorps C4BR, anticorps CD35, anticorps KN, anticorps C3DR, anticorps CD21, anticorps Cr-1, anticorps Cr-2, anticorps Cr1, anticorps CR1-L, anticorps CR2, anticorps CR1, anticorps complement C3b/C4b receptor 1 (Knops blood group), anticorps complement receptor 2, anticorps complement component (3d/Epstein Barr virus) receptor 2, anticorps complement receptor type 1, anticorps CR1, anticorps Cr2, anticorps CR2, anticorps LOC718120
    Poids moléculaire
    210-220kDa
    ID gène
    1378
    UniProt
    P17927
    Pathways
    Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
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