DBN1 anticorps (AA 150-281)

N° du produit ABIN6939227

Cet anticorps anti-DBN1 est un anticorps Souris Monoclonal détectant DBN1 dans IHC et StM. Adapté pour Humain.

Aperçu rapide pour DBN1 anticorps (AA 150-281) (ABIN6939227)

Antigène: DBN1 (Drebrin 1 (DBN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DBN1 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: DBN1-2879

Détail du produit anti-DBN1 anticorps

Épitope: AA 150-281

Immunogène: Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur DBN1

Antigène: DBN1 (Drebrin 1 (DBN1))

Autre désignation: DBN1

Sujet: Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.

Poids moléculaire: 120kDa

ID gène: 1627

UniProt: Q16643

Pathways: Maintenance of Protein Location