FLT1 anticorps

N° du produit ABIN6939405

Détail du produit anti-FLT1 anticorps

Antigène: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FLT1 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Purification: Purified by Protein A/G

Immunogène: Recombinant human VEGF-R1 protein

Clone: FLT1-658

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: 293FT or A431 cells. Cerebellum or skin cancer.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Functional Studies (Order Ab without BSA & Azide), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur FLT1

Antigène: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Autre désignation: FLT1 (FLT1 Produits)

Synonymes: anticorps FLT, anticorps FLT-1, anticorps VEGFR-1, anticorps VEGFR1, anticorps FLT1, anticorps flt1b, anticorps sFlt1, anticorps AI323757, anticorps Flt-1, anticorps fms related tyrosine kinase 1, anticorps FMS-related tyrosine kinase 1, anticorps vascular endothelial growth factor receptor 1, anticorps fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), anticorps FMS-like tyrosine kinase 1, anticorps vascular endothelial growth factor receptor-1, anticorps FLT1, anticorps Flt1, anticorps CpipJ_CPIJ012087, anticorps flt1, anticorps FLT-1

Sujet: Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.

Poids moléculaire: 150-180kDa

ID gène: 2321

UniProt: P17948

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals