Fibronectin 1 anticorps (AA 467-595)
Aperçu rapide pour Fibronectin 1 anticorps (AA 467-595) (ABIN6939415)
Antigène
Voir toutes Fibronectin 1 (FN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 467-595
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Specificité
- Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin.
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Purification
- Purified by Protein A/G
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Immunogène
- Recombinant fragment (around aa 467-595) of human fibronectin protein (exact sequence is proprietary)
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Isotype
- IgG1 kappa
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Indications d'application
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Positive Control: SW156 cells or Kidney.
Known Application: ELISA (For coating, order Ab without BSA),Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- 10 mM PBS with0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Fibronectin 1 (FN1)
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Autre désignation
- FN1
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Poids moléculaire
- 220kDa (monomer), 440kDa (dimer)
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ID gène
- 2335
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UniProt
- P02751
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy
Antigène
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