Annexin a1 anticorps

N° du produit ABIN6939603

Cet anticorps anti-Annexin a1 est un anticorps Souris Monoclonal détectant Annexin a1 dans IHC, FACS et StM. Adapté pour Humain.

Aperçu rapide pour Annexin a1 anticorps (ABIN6939603)

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Annexin a1 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)

Clone: ANXA1-1671

Détail du produit anti-Annexin a1 anticorps

Purification: Purified by Protein A/G

Immunogène: Recombinant full length human Annexin A1 protein

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: A431 and K562 cell lysates, human esophagus, placenta and prostate tissues.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Annexin a1

Antigène: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Autre désignation: ANXA1

Sujet: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Poids moléculaire: 35kDa

ID gène: 301

UniProt: P04083

Pathways: Hormone Transport