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IGKC anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement IGKC dans IHC, WB, FACS et IF. Il présente une réactivité avec des échantillons de Humain.
N° du produit ABIN6939745
639,45 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 10 jours ouvrables

Aperçu rapide pour IGKC anticorps (ABIN6939745)

Antigène

IGKC (Immunoglobulin kappa Constant (IGKC))

Reactivité

Humain

Hôte

  • 22
  • 10
Souris

Clonalité

  • 24
  • 8
Monoclonal

Conjugué

  • 19
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp IGKC est non-conjugé

Application

  • 20
  • 15
  • 8
  • 7
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone

KLC264
  • Fonction

    Kappa Light Chain (B-Cell Marker) Antibody

    Specificité

    This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

    Purification

    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

    Immunogène

    Recombinant human Ig kappa chain

    Isotype

    IgG1, kappa
  • Indications d'application

    Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    Known Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Date de péremption

    24 months
  • Antigène

    IGKC (Immunoglobulin kappa Constant (IGKC))

    Autre désignation

    IGKC

    Sujet

    HCAK1, Ig Kappa Chain C Region, IGKC, Immunoglobulin KM

    293T, Raji or hPBL cells. Human tonsil or spleen.

    Poids moléculaire

    ~22.5kDa

    ID gène

    3514, 449609

    UniProt

    P01601
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