IGKC anticorps (AA 1-107)

N° du produit ABIN7156094

Détail du produit anti-IGKC anticorps

Antigène: IGKC (Immunoglobulin kappa Constant (IGKC))

Épitope: AA 1-107

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGKC est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Immunoglobulin kappa constant protein (1-107AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IGKC

Antigène: IGKC (Immunoglobulin kappa Constant (IGKC))

Autre désignation: IGKC (IGKC Produits)

Synonymes: anticorps HCAK1, anticorps IGKCD, anticorps Km, anticorps IGKC, anticorps Igk-C, anticorps immunoglobulin kappa constant, anticorps immunoglobulin kappa constant L homeolog, anticorps IGKC, anticorps LOC708048, anticorps igkc, anticorps igkc.L, anticorps Igkc

Sujet:

Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).

Aliases: IGKCImmunoglobulin kappa constant antibody, Ig kappa chain C region antibody, Ig kappa chain C region AG antibody, Ig kappa chain C region CUM antibody, Ig kappa chain C region EU antibody, Ig kappa chain C region OU antibody, Ig kappa chain C region ROY antibody, Ig kappa chain C region TI antibody

UniProt: P01834