JUP anticorps

N° du produit ABIN6939839

L’anticorps anti-JUP Monoclonal Souris est utilisé pour la détection de JUP dans des échantillons de Humain, Souris, Rat, Poulet, Chien, Boeuf (Vache) et Cat. Il a été validé pour WB, IF, IHC, FACS et ELISA.

Aperçu rapide pour JUP anticorps (ABIN6939839)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain, Souris, Rat, Poulet, Chien, Boeuf (Vache), Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Clone: 15F11

Détail du produit anti-JUP anticorps

Fonction: Catenin, gamma (Cardiomyocyte Marker) Antibody

Specificité: It recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (°™, æ, Á and 79oΩL) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. °™ T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. °™ T-catenin binds to °™ E-catenin as well as to æ-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for °™-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant, full length chicken Catenin gamma protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Positive Control: HeLa, SK-BR3, A431, HT20, 293, HepG2, A549 or MCF-7 cells. Skin.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1.0 μg/mL)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: JUP

Sujet:

ARVD12, Catenin (cadherin-associated protein), gamma 80 kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB

HeLa, SK-BR3 or MCF-7 cells.

Poids moléculaire: 80-87kDa

ID gène: 3728, 514174

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location