LHCGR anticorps (AA 70-410)

N° du produit ABIN6939964

L’anticorps Souris Monoclonal anti-LHCGR a été validé pour WB, FACS, ELISA et Coat. Il convient pour détecter LHCGR dans des échantillons de Humain.

Aperçu rapide pour LHCGR anticorps (AA 70-410) (ABIN6939964)

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LHCGR est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Coating (Coat)

Clone: LHCGR-1417

Détail du produit anti-LHCGR anticorps

Épitope: AA 70-410

Specificité: Recognizes a protein of 78-85 kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment (around aa 70-410) of human LHCGR protein (exact sequence is proprietary)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: HepG2 or Jurkat cells. Ovarian Carcinoma.

Known Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur LHCGR

Antigène: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Autre désignation: LHCGR

Poids moléculaire: 78-85kDa

ID gène: 3973

UniProt: P22888

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling