PAX6 anticorps (N-Term)

N° du produit ABIN6940257

L’anticorps Souris Monoclonal anti-PAX6 a été validé pour WB, IF et FACS. Il convient pour détecter PAX6 dans des échantillons de Humain, Souris, Rat et Poulet.

Aperçu rapide pour PAX6 anticorps (N-Term) (ABIN6940257)

Antigène: PAX6 (Paired Box 6 (PAX6))

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PAX6 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PAX6-498

Détail du produit anti-PAX6 anticorps

Épitope: AA 1-300, N-Term

Specificité: Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment (N-terminus, aa 1-300) of human PAX6 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Pancreas or Cerebellum.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PAX6

Antigène: PAX6 (Paired Box 6 (PAX6))

Autre désignation: PAX6

Poids moléculaire: 47kDa

ID gène: 5080

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis