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Prohibitin anticorps (AA 167-261)

PHB Reactivité: Humain WB, IHC, StM Hôte: Souris Monoclonal PHB-3230 unconjugated
N° du produit ABIN6940300
  • Antigène Voir toutes Prohibitin (PHB) Anticorps
    Prohibitin (PHB)
    Épitope
    • 16
    • 13
    • 12
    • 11
    • 9
    • 9
    • 9
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 167-261
    Reactivité
    • 136
    • 62
    • 60
    • 11
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 116
    • 20
    Souris
    Clonalité
    • 105
    • 31
    Monoclonal
    Conjugué
    • 69
    • 12
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Prohibitin est non-conjugé
    Application
    • 104
    • 51
    • 45
    • 27
    • 22
    • 22
    • 14
    • 13
    • 11
    • 9
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
    Specificité
    Recognizes a protein of 30 kDa which is identified as Prohibitin, an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. Prohibitin is an ideal mitochondrial marker. It shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant human PHB protein fragment (aa167-261) (exact sequence is proprietary)
    Clone
    PHB-3230
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product PHB Anticorps primaire
  • Indications d'application

    Positive Control: Liver, Kidney, Heart or Endometrium (IHC).

    Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    Prohibitin (PHB)
    Autre désignation
    PHB (PHB Produits)
    Synonymes
    anticorps phb1, anticorps MGC75944, anticorps PHB, anticorps Phb, anticorps ACYPI000080, anticorps phb, anticorps PHB1, anticorps Bap32, anticorps sr:nyz128, anticorps wu:fa18f07, anticorps wu:fb09f05, anticorps prohibitin1, anticorps xphb1, anticorps prohibitin, anticorps prohibitin-2, anticorps prohibitin L homeolog, anticorps PHB, anticorps phb, anticorps LOC484431, anticorps LOC5576054, anticorps Phb, anticorps phb.L
    Poids moléculaire
    30kDa
    ID gène
    5245
    UniProt
    P35232
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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