PODXL anticorps (AA 310-447)

N° du produit ABIN6940330

Détail du produit anti-PODXL anticorps

Antigène: PODXL (Podocalyxin-Like (PODXL))

Épitope: AA 310-447

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PODXL est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Purification: Purified by Protein A/G

Immunogène: Recombinant fragment of human Podocalyxin (around aa 310-447) (exact sequence is proprietary)

Clone: PODXL-2185

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: HeLa, Raji or Jurkat cells. Angiosarcoma, Breast, Prostate, Liver, Pancreatic, Kidney (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PODXL

Antigène: PODXL (Podocalyxin-Like (PODXL))

Autre désignation: PODXL (PODXL Produits)

Synonymes: anticorps Gp200, anticorps PC, anticorps PCLP, anticorps PCLP-1, anticorps PCB, anticorps AW121214, anticorps Ly102, anticorps Pclp1, anticorps podocalyxin, anticorps MEP21, anticorps PODXL, anticorps Gp135, anticorps PCLP1, anticorps cPCLP1, anticorps podxl, anticorps fc18d02, anticorps wu:fc18d02, anticorps Pc, anticorps Pcb, anticorps Podxl, anticorps podocalyxin like, anticorps pyruvate carboxylase, anticorps podocalyxin-like, anticorps PODXL, anticorps PC, anticorps Podxl, anticorps podxl, anticorps Pcx

Sujet: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

Poids moléculaire: 165-170kDa

ID gène: 5420

UniProt: O00592

Pathways: Tube Formation