RNLS anticorps (AA 34-235)

N° du produit ABIN6940382

Cet anticorps anti-RNLS est un anticorps Souris Monoclonal détectant RNLS dans ELISA et Coat. Adapté pour Humain.

Aperçu rapide pour RNLS anticorps (AA 34-235) (ABIN6940382)

Antigène: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RNLS est non-conjugé

Application: ELISA, Coating (Coat)

Clone: RNLS-1940

Détail du produit anti-RNLS anticorps

Épitope: AA 34-235

Purification: Purified by Protein A/G

Immunogène: Recombinant human RNLS protein fragment (around aa 34-235) (exact sequence is proprietary)

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: 293T cells. Heart or Kidney.

Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur RNLS

Antigène: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Autre désignation: RNLS

Sujet: Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events.

Poids moléculaire: 38kDa

ID gène: 55328

UniProt: Q5VYX0