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Prolactin Receptor anticorps

Cet anticorps anti-Prolactin Receptor est un anticorps Souris Monoclonal détectant Prolactin Receptor dans IHC, FACS, IF, IHC (p) et StM. Adapté pour Humain.
N° du produit ABIN6940404

Aperçu rapide pour Prolactin Receptor anticorps (ABIN6940404)

Antigène

Voir toutes Prolactin Receptor (PRLR) Anticorps
Prolactin Receptor (PRLR)

Reactivité

  • 100
  • 32
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Humain

Hôte

  • 59
  • 42
  • 5
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Souris

Clonalité

  • 57
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Monoclonal

Conjugué

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Cet anticorp Prolactin Receptor est non-conjugé

Application

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Staining Methods (StM)

Clone

SPM213
  • Specificité

    It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

    Purification

    Purified by Protein A/G

    Immunogène

    Semi-Purified human prolactin receptor

    Isotype

    IgG1 kappa
  • Indications d'application

    Positive Control: Breast, placenta, liver or pancreas.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin/paraffin tissues requires digestion of tissue sections with pepsin at 1 mg/mL Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37C.)Optimal dilution for a specific application should be determined.

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Date de péremption

    24 months
  • Antigène

    Prolactin Receptor (PRLR)

    Autre désignation

    PRLR

    Poids moléculaire

    70kDa

    ID gène

    5618

    UniProt

    P16471

    Pathways

    Signalistation JAK/STAT, Response to Growth Hormone Stimulus
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