Recombinant Prolactin Receptor anticorps
Aperçu rapide pour Recombinant Prolactin Receptor anticorps (ABIN6940408)
Antigène
Voir toutes Prolactin Receptor (PRLR) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.
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Purification
- Purified by Protein A/G
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Immunogène
- Recombinant full-length human PRLR protein
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Isotype
- IgG
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Indications d'application
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Positive Control: Testicular Carcinoma.
Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. ,Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Prolactin Receptor (PRLR)
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Autre désignation
- PRLR
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Poids moléculaire
- 70kDa
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ID gène
- 5618
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UniProt
- P16471
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Pathways
- Signalistation JAK/STAT, Response to Growth Hormone Stimulus
Antigène
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