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CD147 anticorps

Cet anticorps anti-CD147 est un anticorps Souris Monoclonal détectant CD147 dans IHC et StM. Adapté pour Humain.
N° du produit ABIN6940676

Aperçu rapide pour CD147 anticorps (ABIN6940676)

Antigène

Voir toutes CD147 (BSG) Anticorps
CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivité

  • 176
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  • 4
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  • 2
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Humain

Hôte

  • 101
  • 91
  • 9
  • 1
Souris

Clonalité

  • 125
  • 72
  • 4
Monoclonal

Conjugué

  • 106
  • 14
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  • 7
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Cet anticorp CD147 est non-conjugé

Application

  • 115
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Immunohistochemistry (IHC), Staining Methods (StM)

Clone

BSG-963
  • Specificité

    This MAb recognizes extracellular epitope of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

    Purification

    Purified by Protein A/G

    Immunogène

    Recombinant human BSG protein

    Isotype

    IgG1 kappa
  • Indications d'application

    Positive Control: HSB2 cells. Renal Cell, Colon or Testicular carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-80 °C

    Stockage commentaire

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Date de péremption

    24 months
  • Antigène

    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

    Autre désignation

    BSG

    Poids moléculaire

    35kDa (non-reduced), 40kDa (reduced)

    ID gène

    682

    UniProt

    P35613

    Pathways

    S100 Proteins
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