Transferrin Receptor anticorps

N° du produit ABIN6940695

Cet anticorps Souris Monoclonal détecte spécifiquement Transferrin Receptor dans FACS, ELISA, IF et Coat. Il présente une réactivité envers Humain.

Aperçu rapide pour Transferrin Receptor anticorps (ABIN6940695)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Coating (Coat)

Clone: 66IG10

Détail du produit anti-Transferrin Receptor anticorps

Specificité: It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Purification: Purified by Protein A/G

Immunogène: Human thymocytes (T-cells)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: TFRC

Poids moléculaire: 85-95kDa (monomer), 190kDa (dimer)

ID gène: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis