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Recombinant GRP94 anticorps

HSP90B1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet, Hamster, Chien, Lapin, Porc, Cobaye, Singe, Mouton, Cheval, Xenopus laevis IHC, FACS, StM Hôte: Lapin Monoclonal HSP90B1-3168R unconjugated Recombinant Antibody
N° du produit ABIN6940801
  • Antigène Voir toutes GRP94 (HSP90B1) Anticorps
    GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 132
    • 85
    • 54
    • 39
    • 34
    • 30
    • 29
    • 29
    • 27
    • 27
    • 25
    • 25
    • 24
    • 16
    • 10
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Poulet, Hamster, Chien, Lapin, Porc, Cobaye, Singe, Mouton, Cheval, Xenopus laevis
    Hôte
    • 92
    • 40
    • 24
    • 2
    • 1
    Lapin
    Clonalité
    • 94
    • 65
    Monoclonal
    Conjugué
    • 69
    • 12
    • 11
    • 11
    • 10
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GRP94 est non-conjugé
    Application
    • 152
    • 82
    • 69
    • 62
    • 49
    • 46
    • 39
    • 21
    • 13
    • 13
    • 12
    • 11
    • 4
    • 4
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)
    Specificité
    Recognizes a protein of 94 kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp's are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant full-length human HSP90B1 protein
    Clone
    HSP90B1-3168R
    Isotype
    IgG
    Top Product
    Discover our top product HSP90B1 Anticorps primaire
  • Indications d'application

    Positive Control: HepG2, U20S cells. About 50 % of breast tumors express grp94 protein.

    Known Application: Flow Cytometry (0.5-1 μg/million cells),Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
    Autre désignation
    HSP90B1 (HSP90B1 Produits)
    Synonymes
    anticorps ecgp, anticorps gp96, anticorps tra1, anticorps grp94, anticorps DDBDRAFT_0206450, anticorps DDBDRAFT_0215015, anticorps DDB_0206450, anticorps DDB_0215015, anticorps TRA1, anticorps HSP90B1, anticorps ERp99, anticorps GRP94, anticorps TA-3, anticorps Targ2, anticorps Tra-1, anticorps Tra1, anticorps endoplasmin, anticorps GP96, anticorps fb61d09, anticorps tra-1, anticorps wu:fb61d09, anticorps wu:fq25g01, anticorps Grp94, anticorps ECGP, anticorps Gp96, anticorps ppk98, anticorps hsp108, anticorps heat shock protein 90kDa beta (Grp94), member 1, anticorps heat shock protein Hsp90 family protein, anticorps 94 kD glucose-regulated protein, anticorps heat shock protein 90 beta family member 1, anticorps heat shock protein 90, beta (Grp94), member 1, anticorps heat shock protein 90, beta (grp94), member 1, anticorps heat shock protein 90kDa beta family member 1 L homeolog, anticorps hsp90b1, anticorps grp94, anticorps HSP90B1, anticorps Hsp90b1, anticorps hsp90b1.L
    Poids moléculaire
    94kDa
    ID gène
    7184
    UniProt
    P14625
    Pathways
    Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades
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