SUMO1 anticorps

N° du produit ABIN6940847

Détail du produit anti-SUMO1 anticorps

Antigène: SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SUMO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)

Specificité: This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane.

Réactivité croisée (Details): Predicted to show a broad species reactivity.

Purification: Purified by Protein A/G

Immunogène: Recombinant human SUMO1 protein

Clone: SM1-495

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Breast Carcinoma.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur SUMO1

Antigène: SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

Autre désignation: SUMO1 (SUMO1 Produits)

Synonymes: anticorps DAP1, anticorps GMP1, anticorps OFC10, anticorps PIC1, anticorps SENP2, anticorps SMT3, anticorps SMT3C, anticorps SMT3H3, anticorps UBL1, anticorps hm:zeh0670, anticorps wu:fb74c02, anticorps wu:fd12c02, anticorps zgc:65934, anticorps zgc:85634, anticorps SUMO1, anticorps dap1, anticorps gmp1, anticorps ofc10, anticorps pic1, anticorps senp2, anticorps smt3, anticorps smt3c, anticorps sumo-1, anticorps sumo1, anticorps ubl1, anticorps xsumo-1, anticorps xsumo1, anticorps ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1, anticorps ATSUMO1, anticorps F10M23.180, anticorps F10M23_180, anticorps SMALL UBIQUITIN-LIKE MODIFIER 1, anticorps SUM1, anticorps SUMO 1, anticorps small ubiquitin-like modifier 1, anticorps pigSUMO1, anticorps SENTRIN, anticorps SMTP3, anticorps SUMO-1, anticorps Smt3C, anticorps Ubl1, anticorps small ubiquitin-like modifier 1, anticorps small ubiquitin-like modifier 1 S homeolog, anticorps small ubiquitin-related protein 1, anticorps SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), anticorps SMT3 suppressor of mif two 3 homolog 1 (yeast), anticorps small ubiquitin-like modifier 1 L homeolog, anticorps Sumo1, anticorps SUMO1, anticorps sumo1, anticorps sumo1.S, anticorps sumo-1, anticorps sumo1.L

Poids moléculaire: 11.5kDa (Monomer), 90kDa (Heteromer)

ID gène: 7341

UniProt: P63165

Pathways: M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway