Recombinant CA9 anticorps

N° du produit ABIN6940922

L’anticorps Lapin Monoclonal anti-CA9 a été validé pour IHC et StM. Il convient pour détecter CA9 dans des échantillons de Humain et Cheval.

Aperçu rapide pour Recombinant CA9 anticorps (ABIN6940922)

Antigène: CA9 (Carbonic Anhydrase IX (CA9))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Cheval

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CA9 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: CA9-2993R

Détail du produit anti-CA9 anticorps

Specificité: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human CA9 protein

Isotype: IgG

Information d'application

Indications d'application:

Positive Control: Normal kidney or renal cell carcinoma (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CA9

Antigène: CA9 (Carbonic Anhydrase IX (CA9))

Autre désignation: CA9

Poids moléculaire: 55kDa

ID gène: 768

UniProt: Q16790