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TNFSF9 anticorps (Tumor Necrosis Factor (Ligand) Superfamily, Member 9) Primary Antibody

TNFSF9 Reactivité: Humain FACS, IHC, StM Hôte: Souris Monoclonal CD137L-1547 unconjugated
N° du produit ABIN6940973
$494.31
Plus shipping costs $45.00
100 μg ABIN6940973
100 μg ABIN6940973
local_shipping Destination: Etats-Unis
Envoi sous 2 à 4 jours ouvrables
  • Antigène
    TNFSF9
    Reactivité
    Humain
    • 71
    • 21
    • 5
    Hôte
    Souris
    Clonalité
    Monoclonal
    Conjugué
    Cet anticorp TNFSF9 est non-conjugé
    • 43
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Staining Methods (StM)
    • 50
    • 42
    • 38
    • 14
    • 13
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant full-length human CD137L protein
    Clone
    CD137L-1547
    Isotype
    IgG2a kappa
  • Indications d'application

    Positive Control: Raji, 293T, HEK293 cells. Kidney.

    Known Application: Flow Cytometry (1-2 μg/million cells in 0.1ml), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    TNFSF9
    Autre désignation
    TNFSF9 (TNFSF9 Antibody Extrait)
    Synonymes
    TNFSF9, 4-1BB-L, 4-1BBL, AI848817, Cd137l, Ly63l, CD137L, TNF superfamily member 9, tumor necrosis factor (ligand) superfamily, member 9, Tnfsf9, LOC476729, TNFSF9
    Sujet
    TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
    Poids moléculaire
    27kDa
    ID gène
    8744
    UniProt
    P41273
    Pathways
    Activated T Cell Proliferation, Cancer Immune Checkpoints
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