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ACTN2 anticorps (AA 557-692)

ACTN2 Reactivité: Humain WB, IHC, StM Hôte: Souris Monoclonal ACTN2-3293 unconjugated
N° du produit ABIN6940980
  • Antigène Voir toutes ACTN2 Anticorps
    ACTN2 (Actinin, alpha 2 (ACTN2))
    Épitope
    • 15
    • 13
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    AA 557-692
    Reactivité
    • 64
    • 52
    • 34
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 77
    • 10
    Souris
    Clonalité
    • 66
    • 21
    Monoclonal
    Conjugué
    • 42
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ACTN2 est non-conjugé
    Application
    • 68
    • 21
    • 21
    • 14
    • 14
    • 13
    • 12
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogène
    A recombinant fragment (aa557-692) of human ACTN2 protein (exact sequence is proprietary)
    Clone
    ACTN2-3293
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ACTN2 Anticorps primaire
  • Indications d'application

    Positive Control: Skeletal or Cardiac Muscle.

    Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    ACTN2 (Actinin, alpha 2 (ACTN2))
    Autre désignation
    ACTN2 (ACTN2 Produits)
    Synonymes
    anticorps MGC89234, anticorps ACTN2, anticorps 1110008F24Rik, anticorps CMD1AA, anticorps wu:fd44c03, anticorps zgc:123223, anticorps actinin alpha 2, anticorps actinin, alpha 2b, anticorps actinin alpha 2 S homeolog, anticorps actn2, anticorps ACTN2, anticorps Actn2, anticorps actn2b, anticorps actn2.S
    Sujet
    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    103kDa
    ID gène
    88
    UniProt
    P35609
    Pathways
    Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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