CD8 alpha anticorps (C-Term, Cytoplasmic Domain)

N° du produit ABIN6941082

Cet anticorps anti-CD8 alpha est un anticorps Lapin Polyclonal détectant CD8 alpha dans ELISA et Coat. Adapté pour Humain.

Aperçu rapide pour CD8 alpha anticorps (C-Term, Cytoplasmic Domain) (ABIN6941082)

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD8 alpha est non-conjugé

Application: ELISA, Coating (Coat)

Détail du produit anti-CD8 alpha anticorps

Épitope: C-Term, Cytoplasmic Domain

Immunogène: Recombinant fragment from C-terminal cytoplasmic domain of alpha chain of human CD8 (exact sequence is proprietary).

Isotype: IgG

Information d'application

Indications d'application:

Positive Control: HuT78 or hPBL. Tonsil.

Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 200 µg/mL of antibody Purified from rabbit anti-serum by Protein A chromatography. Supplied in 10 mM PBS, pH 7.4 with 0.05 % BSA and 0.05 % sodium azide. Contact us if you require this antibody in a different format.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD8 alpha

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8A

Sujet: CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cell express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.

Poids moléculaire: 32kDa

ID gène: 925

UniProt: P01732

Pathways: TCR Signaling