NAPSA anticorps (AA 189-299)

N° du produit ABIN6941163

L’anticorps anti-NAPSA Monoclonal Souris est utilisé pour la détection de NAPSA dans des échantillons de Humain. Il a été validé pour IHC, WB, IF et FACS.

Aperçu rapide pour NAPSA anticorps (AA 189-299) (ABIN6941163)

Antigène: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NAPSA est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: NAPSA-1238-NAPSA-1239

Détail du produit anti-NAPSA anticorps

Épitope: AA 189-299

Fonction: Napsin A (Lung Adenocarcinoma Marker) Antibody

Specificité: Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Purification: 200ug/ml of Ab Purified from rabbit anti-serum by Protein A.

Immunogène: Recombinant human Napsin-A protein fragment (aa189-299) (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application:

Positive Control: Lung adenocarcinoma.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL for 60 minutes at RT), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur NAPSA

Antigène: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Autre désignation: NAPSA

Sujet:

ASP4, Aspartyl protease 4, KAP, Kidney derived aspartic protease like protein (Kdap), NAP1, NAPA, Napsa, napsin A aspartic peptidase, Pronapsin A, SNAPA

Lung adenocarcinoma.

Poids moléculaire: 37kDa

ID gène: 9476, 512843

UniProt: O96009

Pathways: Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis