CHAF1A anticorps

N° du produit ABIN6942547

L’anticorps anti-CHAF1A Monoclonal produit chez le Lapin a été validé pour WB, IP, IF (p), IHC (p), FACS et IF (cc). Il convient pour la détection de CHAF1A dans des échantillons provenant de Humain. }

Aperçu rapide pour CHAF1A anticorps (ABIN6942547)

Antigène: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CHAF1A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 1D4

Détail du produit anti-CHAF1A anticorps

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Recombinant protein within human p150 CAF1 aa 100-300.

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CHAF1A

Antigène: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Autre désignation: CHAF1A

Sujet:

Synonyms: Chromatin assembly factor 1 subunit A, Chromatin assembly factor I p150 subunit, CAF-1 subunit A, CAF-I 150 kDa subunit, CAF-I p150, hp150, p150 CAF1

Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.

ID gène: 10036

UniProt: Q13111