CHAF1A anticorps (Internal Region)

N° du produit ABIN6257706

Détail du produit anti-CHAF1A anticorps

Antigène: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHAF1A est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: CAF1A Antibody detects endogenous levels of total CAF1A.

Homologie: Bovine,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CAF1A, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CHAF1A

Antigène: CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))

Autre désignation: CHAF1A (CHAF1A Produits)

Synonymes: anticorps CHAF1A, anticorps CAF-1, anticorps CAF1, anticorps CAF1B, anticorps CAF1P150, anticorps P150, anticorps AL023013, anticorps AL024058, anticorps Cac1p, anticorps CAF-1P150, anticorps CAF-I-p150, anticorps CAF-Ip150, anticorps caip150, anticorps wu:fd14g10, anticorps zgc:153930, anticorps chaf1a-b, anticorps xp150, anticorps chromatin assembly factor 1 subunit A, anticorps chromatin assembly factor 1, subunit A (p150), anticorps chromatin assembly factor 1 subunit A S homeolog, anticorps Chaf1a, anticorps CHAF1A, anticorps LOC100447657, anticorps chaf1a, anticorps chaf1a.S

Sujet:

Description: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity).

Gene: CHAF1A

Poids moléculaire: 150 kDa

ID gène: 10036

UniProt: Q13111