DENND1A anticorps (AA 42-140) (HRP)

N° du produit ABIN6942843

Cet anticorps Lapin Polyclonal détecte spécifiquement DENND1A dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Rat.

Aperçu rapide pour DENND1A anticorps (AA 42-140) (HRP) (ABIN6942843)

Antigène: DENND1A (DENN/MADD Domain Containing 1A (DENND1A))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DENND1A est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DENND1A anticorps (HRP)

Épitope: AA 42-140

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DENND1A

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DENND1A

Antigène: DENND1A (DENN/MADD Domain Containing 1A (DENND1A))

Autre désignation: DENND1A

Sujet:

Synonyms: Connecdenn 1, Connecdenn, DEN1A_HUMAN, DENN domain-containing protein 1A, DENN/MADD domain containing 1A, dennd1a, FAM31A, FLJ21129, FLJ38464, KIAA1608, OTTHUMP00000022090, Protein FAM31A, RP11 230L22.3.

Background: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]

ID gène: 57706

UniProt: Q8TEH3