HES1 anticorps

N° du produit ABIN6943615

L’anticorps Lapin Monoclonal anti-HES1 a été validé pour WB, IHC, FACS et IF (cc). Il convient pour détecter HES1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HES1 anticorps (ABIN6943615)

Antigène: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HES1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 3F8

Détail du produit anti-HES1 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant human Hes1 between 200 to 300 amino acids

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200
IHC()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur HES1

Antigène: HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

Autre désignation: Hes1

Sujet:

Synonyms: Transcription factor HES-1, Class B basic helix-loop-helix protein 39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, bHLHb39, hHL, HES1

Background: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

ID gène: 3280

UniProt: Q14469

Pathways: Réparation de l'ADN