INSRR anticorps

N° du produit ABIN6943804

L’anticorps anti-INSRR Monoclonal Lapin est utilisé pour la détection de INSRR dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IHC (p).

Aperçu rapide pour INSRR anticorps (ABIN6943804)

Antigène: INSRR (Insulin Receptor-Related Receptor (INSRR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp INSRR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 8A1

Détail du produit anti-INSRR anticorps

Fonction: Insulin Receptor R (8A1) Monoclonal Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: N terminal Human Insulin Receptor R

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IHC-P(1:200-400)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur INSRR

Antigène: INSRR (Insulin Receptor-Related Receptor (INSRR))

Autre désignation: INSRR

Sujet:

Synonyms: Insulin receptor-related protein, IR-related receptor, Insulin receptor-related protein alpha chain, Insulin receptor-related protein beta chain, IRR, INSRR

Background: The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH . Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

ID gène: 3645

UniProt: P14616

Pathways: Signalisation RTK