ILK anticorps (C-Term)

N° du produit ABIN6943814

Cet anticorps anti-ILK Monoclonal Lapin (Clone 3G2) (ABIN6943814) détecte spécifiquement ILK dans WB, FACS, IF (cc) et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ILK anticorps (C-Term) (ABIN6943814)

Antigène: ILK (Integrin-Linked Kinase (ILK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ILK est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3G2

Détail du produit anti-ILK anticorps

Épitope: C-Term

Fonction: Integrin linked ILK (3G2) Monoclonal Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein within Human Integrin linked ILK between 400 amino acids to the C-terminus

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ILK

Antigène: ILK (Integrin-Linked Kinase (ILK))

Autre désignation: Integrin linked ILK

Sujet:

Synonyms: Integrin-linked protein kinase, 59 kDa serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK, ILK

Background: Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

ID gène: 3611

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration