KARS anticorps (C-Term)

N° du produit ABIN6943858

L’anticorps anti-KARS Monoclonal Lapin est utilisé pour la détection de KARS dans des échantillons de Humain. Il a été validé pour WB, IP et IHC (p).

Aperçu rapide pour KARS anticorps (C-Term) (ABIN6943858)

Antigène: KARS (Lysyl-tRNA Synthetase (KARS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp KARS est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1H8

Détail du produit anti-KARS anticorps

Épitope: C-Term

Fonction: Lysyl-tRNA synthetase (1H8) Monoclonal Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein corresponding to C-terminal human Lysyl tRNA synthetase.

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IHC-P(1:200-400), IP(1-2 μg)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur KARS

Antigène: KARS (Lysyl-tRNA Synthetase (KARS))

Autre désignation: KARS

Sujet:

Synonyms: Lysine tRNA ligase, Lysyl tRNA synthetase, LysRS, KARS, KIAA0070

Background: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity.

ID gène: 3735

UniProt: Q15046