KREMEN2 anticorps (AA 351-450)

N° du produit ABIN6943890

Cet anticorps Lapin Polyclonal détecte spécifiquement KREMEN2 dans WB, ELISA, IF (cc), IF (p), ICC, IHC (fro) et IHC (p). Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour KREMEN2 anticorps (AA 351-450) (ABIN6943890)

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KREMEN2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-KREMEN2 anticorps

Épitope: AA 351-450

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KREMEN2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur KREMEN2

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Autre désignation: KREMEN2

Sujet:

Synonyms: Dickkopf receptor 2, KREM2_HUMAN, KREMEN 2, Kremen protein 2, Kremen protein 2 precursor, Kremen2, Kringle containing protein marking the eye and the nose, Kringle containing transmembrane protein 2, Kringle domain containing transmembrane protein 2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose, KRM 2, KRM2, MGC10791, MGC16709.

Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

ID gène: 79412

UniProt: Q8NCW0

Pathways: Signalisation WNT